Distribution of erm genes and low prevalence of inducible resistance to clindamycin among staphylococci isolates
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چکیده
منابع مشابه
Distribution of erm genes and low prevalence of inducible resistance to clindamycin among staphylococci isolates.
INTRODUCTION Resistance to macrolides, lincosamides and streptogramins B (MLS(B) antibiotics) in staphylococci may be due to modification in ribosomal target methylase encoded by erm genes. The expression of MLS(B) resistance lead to three phenotypes, namely constitutive resistance (cMLS(B)), inducible resistance (iMLS(B)), and resistance only to macrolides and streptogramins B (MS(B)). The iML...
متن کاملInducible clindamycin resistance among clinical isolates of Staphylococci.
INTRODUCTION Clinical failure of clindamycin therapy has been reported due to multiple mechanisms that confer resistance to macrolide, lincosamide and streptogramin antibiotics. This study was undertaken to detect the presence of inducible clindamycin resistance among clinical isolates of staphylococci. MATERIALS AND METHODS The detection of inducible clindamycin resistance was performed by D...
متن کاملinducible clindamycin resistance in clinical isolates of staphylococcus aureus due to erm genes, iran.
background and objectives: resistance to macrolide can be mediated by erm and msra genes in staphylococcus aureus . there are the evidences that show erm genes may be causative agent of inducible or constitutive resistance. the aim of this study was to investigate the incidence of inducible clindamycin resistance and determine the most frequency of erm and msr a genes among s. aureus isolates. ...
متن کاملInducible clindamycin resistance in clinical isolates of Staphylococcus aureus due to erm genes, Iran
BACKGROUND AND OBJECTIVES Resistance to macrolide can be mediated by erm and msrA genes in Staphylococcus aureus. There are the evidences that show erm genes may be causative agent of inducible or constitutive resistance. The aim of this study was to investigate the incidence of inducible clindamycin resistance and determine the most frequency of erm and msrA genes among S. aureus isolates. M...
متن کاملInducible clindamycin resistance among Staphylococcus aureus isolates
Introduction: Clindamycin is considered an useful alternate drug in penicillin-allergic patients in the treatment of skin & soft tissue infections caused by Staphylococcus aureus. Staphylococcus spp. can be resistant to erythromycin through either erm or msr A genes. Strains with erm-mediated erythromycin resistance may possess inducible clindamycin resistance but may appear susceptible to clin...
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ژورنال
عنوان ژورنال: The Brazilian Journal of Infectious Diseases
سال: 2010
ISSN: 1413-8670
DOI: 10.1016/s1413-8670(10)70113-6